Bret Payseur | UW Laboratory of Genetics
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Bret Payseur










Associate Professor of Medical Genetics


Ph.D., University of Arizona, 2003
Postdoctoral Research: Cornell University



Address: 2428 Genetics/Biotech
Telephone: 890-0867
E-mail: payseur@wisc.edu

Research Interests:

Population genetics, genetics of speciation and genetics of morphological evolution

Research Fields:

Genomics
Mouse Genetics
Population/Evolution
Human and Mammalian

Research Description:

Exciting new advances in DNA sequencing technology have begun to reveal the depth and significance of genomic variation among organisms.  The causes of this variation are evolutionary, and the rapid accumulation of data on the genomic scale has firmly positioned population and evolutionary geneticists at the center of this biological revolution.  Our research combines the power of genomic data with concepts and tools from population genetics to address long-standing questions about the evolutionary process and the nature of genetic variation.

Topics of interest include:
Genetics of speciation
Evolution of extreme body size on islands
Evolution of recombination rate
Natural selection on rapidly mutating DNA sequences
Sex ratio distortion in hybrids

Representative Publications:


White, M. A., M. A. Stubbings, B. L. Dumont, and B. A. Payseur (2012).  Genetics and evolution of hybrid male sterility in house mice.  Genetics, in press.

Dumont, B. L., and B. A. Payseur (2011).  Genetic analysis of genome-scale recombination rate evolution in house mice.  PLoS Genetics 7:e1002116.

Dumont, B. L., M. A. White, B. Steffy, T. Wiltshire, and B. A. Payseur (2011).  Extensive recombination rate variation in the house mouse species complex inferred from genetic linkage maps.  Genome Research 21:114-125.

Payseur, B. A., P. Jing, and R. J. Haasl (2011).  A genomic portrait of human microsatellite variation.  Molecular Biology and Evolution 28:303-312.

Payseur, B. A. (2010).  Using differential introgression in hybrid zones to identify genomic regions involved in speciation.  Molecular Ecology Resources 10:806-820.

White, M. A., C. AnĂ©, C. N. Dewey, B. R. Larget, and B. A. Payseur (2009).  Fine-scale phylogenetic discordance across the house mouse genome.  PLoS Genetics 5: e1000729.