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Rayla Temin

Emeritus Adjunct Professor of Genetics

Rayla Temin
Address:
4122 Genetics/Biotech
Telephone:
263-2412
Email:
rgtemin@wisc.edu
Research Fields:
Drosophila

Ph.D., University of Wisconsin-Madison, 1963

Research Description

Segregation Distorter (SD) is a meiotic drive gene complex found in natural populations of Drosophila melanogaster. It causes heterozygous SD+/SD males to produce almost exclusively SD sperm. SD was first discovered in Madison about 50 years ago, and much has been learned about its genetic mechanism and molecular basis. The Sd mutant encodes a truncated version of the nuclear transport protein RanGap. I have been studying a dominant suppressor of SD, one that restores the Mendelian ratio, as an entree to defining other steps in the sperm transmission pathway and to further understand the population dynamics of the SD system. Currently, I am conducting a screen for gamma-ray induced revertants of Su(SD) in order to cytologically pinpoint the physical location of the mutation.

Representative Publications

  • Cooper, G. M., Temin, R. G., and B. Sugden.
  • Temin, R. G., B. Ganetzky, P. A. Powers, T. W. Lyttle, S. Pimpinelli, P. Dimitri, C. I. Wu and Y. Hiraizumi. 1991. Segregation distortion in Drosophila melanogaster: genetic and molecular analyses. Am. Nat. 137:287-331.
  • Temin, R. G. 1991. The independent distorting ability of the Enhancer of Segregation Distortion, E(SD), in Drosophila melanogaster. Genetics 128:339-56.
  • Temin, R. G., H. U. Meyer, P. S. Dawson and J. F. Crow. 1969. The influence of epistasis on homozygous viability depression in Drosophila melanogaster. Genetics 61:497-519.