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John Doebley

Professor of Genetics

John Doebley
Lab Home Page:
Doebley Lab
Address:
5320 Genetics/Biotech
Telephone:
265-5803
Email:
jdoebley@wisc.edu
Research Fields:
Plant Genetics
Population/Evolution

Ph.D., University of Wisconsin-Madison, 1980

Postdoctoral Research: North Carolina State University

Research Interests

Evolutionary genetics, development and evolution

Research Description

Our group is trying to understand the genetic basis of the evolution of new morphological traits in plants. How many genes contribute to the evolution of a new trait? Are these genes regulatory or structural? Do the alterations in these genes affect protein function or gene expression? Research in my laboratory addresses these and related questions using maize and its wild relatives as a model system

Representative Publications

  • Weber, A.L., Clark, R.M., Vaughn, L., Sanchez-Gonzalez, J.J., Yu, J., Yandell, B., Bradbury, P. and J.F. Doebley. 2007. Major regulatory genes in maize contribute to standing variation in teosinte (Zea mays ssp. parviglumis). Genetics. 177: 2349-2359.
  • Clark, R., Nussbaum-Wagler, T., Quijada, P. and J. Doebley. 2006. A distant upstream enhancer at the maize domestication gene, tb1, has pleiotropic effects on plant and inflorescent architecture. Nature Genetics. 38: 594-597.
  • Wang, H., Nussbaum-Wagler, T., Li, B., Zhao, Q., Vigouroux, Y., Faller, M., Bomblies, K., Lukens, L. and J. Doebley. 2005. The origin of the naked grains of maize. Nature. 436: 714-719.
  • Bomblies, K., Wang, R.-L., Ambrose, B.A., Schmidt, R.J., Meeley, R.B. and J. Doebley. 2003. Duplicate FLORICAULA/LEAFY homologs zfl1 and zfl2 control inflorescence architecture and flower patterning in maize. Development. 130:2385-2395. .
  • Doebley, J., Stec, A. and L. Hubbard. 1997. The evolution of apical dominance in maize. Nature. 386:485-488.