Course Offerings in Genetics

• 160 Heredity

  (Crosslisted with Botany, Zoology 160.) I; 3 cr (B-E). Heredity; genetics for students not specializing in life sciences; principles of heredity; current advances in genetics applied to humans, animals and plants with their impact on life sciences and society. Lectures and discussion. P: Crse open to all So; Open to Fr with cons inst; HS or college crse in biol recommended; not open to pre-med or sci major without cons inst. Day.

• 299 Independent Study

  1-3 cr. (I) P: Fr, So or Jr st & written cons inst.

• 375 Freshman Seminar – Special Topics

  II, 1 cr. Weekly seminars by specialists in various genetic careers. P: Fr st. Leeds.

• 399 Coordinative Internship/Cooperative Education

  I, II, SS; 1-8 cr. (A) P: So, Jr or Sr st and cons supervising inst, advisor, and internship program coordinator.

• 466 General Genetics

  (Crosslisted with Botany, Zoology 466.) I, II, SS; 3 cr. (B-I) Genetics in eukaryotes and prokaryotes. Includes Mendelian genetics, mapping, molecular genetics, genetic engineering, cytogenetics, quantitative genetics, and population genetics. Illustrative material includes viruses, bacteria, plants, fungi, insects, and humans. P: Algebra, 1 yr chem and 1 yr biology or cons inst. Doebley, Engels, Ganetzky, Kung, Laughon, Leeds, Masson, Pelegri.

• 545 Undergraduate Genetics Laboratory

  I,II; 2 cr. Laboratory projects illustrate: Mendelian genetics, mapping, molecular genetics and genetic engineering. Model systems include: Arabidopsis, Drosophila and yeast. P: Genetics, Botany, Zoology 466 or cons inst. Leeds.

• 561 Introductory Cytogenetics

  (Crosslisted with Botany, Hort 561) II; 2-3 cr. (B-I) Mitotis, meiosis, variations in chromosome structure and number, cytological aspects of hybridity and apomixis; chromosomes as they affect breeding behavior. P: Genetics, Botany, Zoology 466 or cons inst. Jiang.

• 565 Human Genetics

  (Crosslisted with Medical Genetics 565.) I; 3 cr. (B-I) Principles, problems, and methods of human genetics. Surveys aspects of medical genetics, biochemical genetics, molecular genetics, cytogenetics, quantitative genetics, and variation as applied to humans. P: Genet 466 or equiv or cons inst. Payseur, Prolla.

• 566 Advanced Genetics – Capstone

  II; 3 cr. (B-I) Principles of classical and molecular genetic analysis taught through readings in the scientific literature. P: Genetics 466 (or equiv) & genetics major or cons inst. Required of all undergrad genetics majors. Ikeda, Pelegri, Sun, Yin.

• 607 Advanced Microbial Genetics

  (Crosslisted with Bact 607.) I; 3 cr. (B-I) Molecular genetic methods and related aspects of prokaryotic and lower eukaryotic biology, as well as critical analysis of the scientific literature. Approximately two-thirds of the course will focus on prokaryotics and one-third on lower eukaryotic micobes. Lectures cover mutagenesis, conjugation, transformation, transduction, plasmids, cloning and transposable elements. P: Genetics 466 or equiv, Biochem 501 or equiv, & Grad St or cons inst. Roberts.

• 610 Quantitative Genetics

  (Crosslisted with AnSci 610.) I; 3 cr. (B-A) An advanced approach with emphasis on statistical foundations. Classical theory with extensions to maternal and paternal effects. Selection theory is considered in depth. P: Genetics 466 and Statistics 572 or cons inst. Rutledge.

• 612 Prokaryotic Molecular Genetics

  (Crosslisted with Bact, Biochem 612.) I; 3 cr. (B-D) Molecular aspects of viral and bacterial genetics; chromosome structure mutation, transfer of genetic information, DNA replication, recombination, transcription, translation, and regulation of gene activity. P: Genetics 466 or Bact 370 or equiv, & Biochem 501 or equiv, or cons inst. Gourse.

• 629 Evolutionary Genetics (pending)

  (Crosslisted with Med Genet and Botany 629.) I; Odd Years; 3 cr (B-A). Basic principles of phylogenetics, population genetics and quantitative genetics including the construction of gene trees, forces affecting the amount and distribution of genetic variation in populations, and the inheritance and evolution of multifactorial characters. P: Gen 466 or Biocore 301 and 302 or equiv; knowledge of elementary calculus and statistics or consent of instructor. Doebley, Larget, Payseur.

• 655 Biology and Genetics of Filamentous Fungi

  (Crosslisted with Pl Path, Bact, Botany, MM&I).) II; Odd Years; 3-4 cr (A). Fungal genetics, genomics, and physiology using plant pathogenic fungi and the genetic models Aspergillus nidulas and Neurospora crassa as model systems to explore the current knowledge of fungal genetics and plant/fungal inerations. P: Con inst; Pl Path 300 &332 recommendd; Genetics 466 or equiv; general microbial crse. Keller, Yu.

• 677 Advanced Topics in Genetics

  (Crosslisted with Md Genet 677.) I, II; 1-3 cr. Contents vary; consideration of subjects not included in the curriculum. P: Cons inst or Grad st.

• 681 Senior Honors Thesis

  I, II, SS,; 2-4 cr (A). P: Honors candidacy.

• 682 Senior Honors Thesis

  I, II, SS: 2-4 cr (A) Continuation of 681. P: Honors program candidacy and Genetics 681.

• 699 Independent Reading

  I, II; 1-3 cr. (A) P: Cons inst & Sr st.

• 701 Advanced Genetics

  I, 3 cr. This course covers at the graduate level five main topics each comprising lectures with discussion: linkage and mapping, non-Mendelian inheritance, chromosomal phenomena, mutation and screening, and meiosis P: Genetics 466 or equiv Cons inst or Grad st. Culbertson, Engels, Ganetzky, Laughon.

• 703 Eukaryotic Molecular Biology

  (Crosslisted with Biochem) II; 3 cr. (P-A) Eukaryotic cell biology, mainly in animal cells; focuses on the differences in gene activity between cell types and on the assembly and reproduction of subcellular constituents P: Biochem 612 or cons inst. Anderson, Kimble, Wickens.

• 707 Genetic Analysis of Human Biology

  (Crosslisted with Medical Genetics/Oncology) II, Odd Yrs; 3 cr. Contemporary research issues in human biology including cancer are discussed from a genetic viewpoint. Most weeks an invited speaker gives a research lecture and associated reading material from primary literature is discussed with the course faculty and invited speaker. P: Cons inst or Grad st. Ikeda, Yin.

• 708 Genetics of Development

  (Crosslisted with Medical Genet) II, Even Yrs; 3 cr. Contemporary issues in genetic, developmental, cell and molecular biology are addressed in discussion format. Most weeks an invited speaker gives a research lecture. Reading material is taken from the primary literature. The discussion joins the invited speaker and the reading into evaluating genetic approaches to biological problems. This course involves participation in discussion, course research paper and peer and faculty review of a student research paper. P: Cons inst or Grad st. Skop, Sun.

• 731 Clinical Genetics

  (Crosslisted with Genetics, Nursing 731.) I, Even Yrs; 3 cr. Clinical manifestation of human genetic disorders, practical principles of genetic counseling; for students preparing for genetic counseling and other health care professions, e.g., nursing, physician's assistant, etc., in which they will encounter patients/families with genetically determined conditions, disorders, related problems, and prevention. P: Genetics 466 or equiv; Genetics 565 & 561 or 562; or cons inst. Some knowledge of basic medical terminology essential. Pauli.

• 840 Regulatory Mechanisms in Plant Development

  (Crosslisted with Botany, Genetics 840) I; 3 cr. Molecular mechanisms whereby endogenous and environmental regulatory factors control development; emphasis on stimulus perception and primary events in the signal chain leading to modulated gene expression and cellular development; lecture. P: Biochem 501 or 601 & Botany 500 or Biocore 301 & 323.

• 875 Special Topics

• Genome and Proteomic Analysis

  I, 3 cr. This course will present modern techniques in genomics and proteomics, with particular focus on analyzing the data generated by these techniques. Course materials will cover genomic sequencing, comparative sequence analysis, phylogeny construction and phylogenomics, transcription factor motif discovery, DNA microarray analysis, techniques in mass spectrometry, proeomic screening methods, and protein interaction network analysis. Gasch, Perna, Skop

• Plant Genetics

  I, 2 cr. The objective of this course is to cover the basic concepts of genetics and genomics as applied to plants. Possible topics: plant genetics, genomic and proteomic analysis. P: Genetics 466 or equivalent. Masson

• 915 Computational and Informatics in Biology and Medicine

  (Crosslisted with Biostats and Medical Informatics 915, Biomedical Engineering 915, Chemical and Biological Engineering 915, Computer Science 915). I, II. 1 cr. Participants and outside speakers will discuss current research in computation and informatics in biology and medicine. Required of all Computation and Informatics in Biology and Medicine Program Trainees. Prerequisite: Consent of instructors. Pape, Phillips, Shavlik, Blattner, Mitchell.

• 951 Seminar in Animal Breeding

  (Crosslisted with AnSci 951.) I, II; 0-1 cr. P: Cons inst. Weigel.

• 957 Seminar – Plant Breeding

  (Crosslisted with Hort, Agronomy 957.) I, II; 1 cr. P: Grad st. Yandell.

• 990 Research

  1-12 cr. P: Grad st and Cons inst.

• 993 Seminar in Genetics

  I, II; 0-1 cr. Sections deal with various aspects of genetics: Drosophila, maize, immunogenetics, developmental genetics, or other special topics. Students may enroll in two or more sections if they wish. P: Grad st & cons inst.