John Doebley
Professor of Genetics
Ph.D., University of Wisconsin-Madison, 1980
Postdoctoral Research: North Carolina State University
Address: 5320 Genetics/Biotech
Telephone: 265-5803
E-mail: jdoebley@wisc.edu
Research Interests:
Evolutionary genetics, development and evolution
Research Fields:
Plant Genetics
Population/Evolution
Research Description: Our group is trying to understand the genetic basis of the evolution of new morphological traits in plants. How many genes contribute to the evolution of a new trait? Are these genes regulatory or structural? Do the alterations in these genes affect protein function or gene expression? Research in my laboratory addresses these and related questions using maize and its wild relatives as a model system
Representative Publications:
Studer,
A., Q. Zhao, J. Ross-Ibarra, and J. Doebley. 2011. A transposon insertion
was the causative mutation in the maize domestication gene tb1. Nature
Genetics 43: 1160-1163.
Studer,
A., and J. Doebley. 2011. Fractionation of the maize domestication QTL teosinte
branched1. Genetics 188: 673-681.
Zhao,
Z., A. L. Weber, M. D. McMullen, K. Guill, and J. Doebley. 2011.
MADS-box genes of maize: frequent targets of selection during
domestication. Genetical Research 93: 65-75.
Weber,
A. L., W. H. Briggs, J. Rucker, B. M. Baltazar, J. J. Sánchez-Gonzalez, P.
Feng, E. S. Buckler and J. Doebley. 2008. The genetic architecture of
complex traits in teosinte (Zea mays ssp. parviglumis): new
evidence from association mapping. Genetics 180:1221–1232.
Briggs,
W. H., M. Mc Mullen, B. Gaut, and J. F. Doebley. 2007. Linkage mapping of
domestication loci in a large maize-teosinte backcross resource. Genetics
177:1915-28.
Clark,
R, T. Nussbaum-Wagler, P. Quijada and J. Doebley. 2006. A distant
upstream enhancer at the maize domestication gene, tb1, has pleiotropic
effects on plant and inflorescent architecture. Nature Genetics 38:
594-597.
Wang,
H., T. Nussbaum-Wagler, B. Li, Q. Zhao, Y. Vigouroux, M. Faller, K. Bomblies,
L. Lukens, and J. Doebley. 2005. The origin of the naked grains of
maize. Nature 436: 714-719.
Bomblies,
K., R.-L. Wang, B. A. Ambrose, R. J. Schmidt, R. B. Meeley, and J. Doebley.
2003. Duplicate FLORICAULA/LEAFY homologs zfl1 and zfl2
control inflorescence architecture and flower patterning in maize. Development
130:2385-2395.
Vigouroux,
Y., M. McMullen, C. T. Hittinger, K. Houchins, L. Schulz, S. Kresovich, Y.
Matsuoka and J. Doebley. 2002. Identifying genes of agronomic importance in
maize by screening microsatellites for evidence of selection during
domestication. Proc. Natl. Acad. Sci. USA 99:9650-9655.
Matsuoka,
Y., Y. Vigouroux, M. M. Goodman, J. Sanchez G., E. Buckler and J. Doebley.
2002. A single domestication for maize shown by multilocus microsatellite
genotyping. Proc. Natl. Acad. Sci. USA 99:8060-8064.
Professor of Genetics
Ph.D., University of Wisconsin-Madison, 1980
Postdoctoral Research: North Carolina State University
Address: 5320 Genetics/Biotech
Telephone: 265-5803
E-mail: jdoebley@wisc.edu
Research Interests:
Evolutionary genetics, development and evolution
Research Fields:
Plant Genetics
Population/Evolution
Our group is trying to understand the genetic basis of the evolution of new morphological traits in plants. How many genes contribute to the evolution of a new trait? Are these genes regulatory or structural? Do the alterations in these genes affect protein function or gene expression? Research in my laboratory addresses these and related questions using maize and its wild relatives as a model system
Studer, A., Q. Zhao, J. Ross-Ibarra, and J. Doebley. 2011. A transposon insertion was the causative mutation in the maize domestication gene tb1. Nature Genetics 43: 1160-1163.
Studer, A., and J. Doebley. 2011. Fractionation of the maize domestication QTL teosinte branched1. Genetics 188: 673-681.
Zhao, Z., A. L. Weber, M. D. McMullen, K. Guill, and J. Doebley. 2011. MADS-box genes of maize: frequent targets of selection during domestication. Genetical Research 93: 65-75.
Weber, A. L., W. H. Briggs, J. Rucker, B. M. Baltazar, J. J. Sánchez-Gonzalez, P. Feng, E. S. Buckler and J. Doebley. 2008. The genetic architecture of complex traits in teosinte (Zea mays ssp. parviglumis): new evidence from association mapping. Genetics 180:1221–1232.
Briggs, W. H., M. Mc Mullen, B. Gaut, and J. F. Doebley. 2007. Linkage mapping of domestication loci in a large maize-teosinte backcross resource. Genetics 177:1915-28.
Clark, R, T. Nussbaum-Wagler, P. Quijada and J. Doebley. 2006. A distant upstream enhancer at the maize domestication gene, tb1, has pleiotropic effects on plant and inflorescent architecture. Nature Genetics 38: 594-597.
Wang, H., T. Nussbaum-Wagler, B. Li, Q. Zhao, Y. Vigouroux, M. Faller, K. Bomblies, L. Lukens, and J. Doebley. 2005. The origin of the naked grains of maize. Nature 436: 714-719.
Bomblies, K., R.-L. Wang, B. A. Ambrose, R. J. Schmidt, R. B. Meeley, and J. Doebley. 2003. Duplicate FLORICAULA/LEAFY homologs zfl1 and zfl2 control inflorescence architecture and flower patterning in maize. Development 130:2385-2395.
Vigouroux, Y., M. McMullen, C. T. Hittinger, K. Houchins, L. Schulz, S. Kresovich, Y. Matsuoka and J. Doebley. 2002. Identifying genes of agronomic importance in maize by screening microsatellites for evidence of selection during domestication. Proc. Natl. Acad. Sci. USA 99:9650-9655.
Matsuoka, Y., Y. Vigouroux, M. M. Goodman, J. Sanchez G., E. Buckler and J. Doebley. 2002. A single domestication for maize shown by multilocus microsatellite genotyping. Proc. Natl. Acad. Sci. USA 99:8060-8064.
